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The recommended approach is to try conservative management strategies first (cool compresses, antihistamines, clothing changes), then consider dose adjustment if symptoms persist beyond 4 weeks, and only discuss discontinuation if symptoms are severe and unresponsive to other interventions

doi: 10.1155/2024/7254066 13

Pitts MW, Kremer PM, Hashimoto AC, Torres DJ, Byrns CN, Williams CS et al

Ive had IV therapy with Gazala and laser treatment here, and both have been excellent

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