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Diabetes and Hypertension: A Position Statement by the American Diabetes Association
These therapies support cellular function, energy production, detoxification, immune balance, and skin vitality, making them an essential part of modern wellness programs
Adults are expected to lead the end user segment with a 65% market share in 2025
From a pharmacological safety perspective, the adverse effect profile of retatrutide based on Phase 1 and Phase 2 clinical trial data (including the NEJM 2023 Phase 2 trial) includes: Gastrointestinal effects: Nausea, vomiting, diarrhoea, and constipation (the most commonly reported side effects in trial participants) Injection site reactions: Redness, swelling, or discomfort at the injection site Cardiovascular effects: Increases in heart rate have been observed in trial participants [21] [22] Hypoglycaemia: Particularly relevant in individuals with diabetes or those taking insulin, sulfonylureas, or other glucose-lowering agents Potential thyroid effects: GLP-1 receptor agonists have been associated with thyroid C-cell changes in rodent studies
Both of these subsets need a ton more data such as patients who stopped using CPAP machines due to sleep apnea resolution, change in amount of daily pain medication taken in the arthritis basket, etc
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