Although these data appear to conflict with our observation that tirzepatide stimulates alpha cell activity, it is important to note that the metabolic profile of the subjects in the tirzepatide arm improved dramatically during the 28-week period, complicating interpretations
doi: 10.3389/fphar.2026.1795229 Received 24 January 2026 Revised 14 March 2026 Accepted 18 March 2026 Published 14 April 2026 Volume 17 - 2026 Edited by Narasaiah Kolliputi, University of South Florida, United States Reviewed by Inas Youssef Younis, Cairo University, Egypt Venkata Tulasiramu Ponnada, Collins Florida, United States Updates Copyright 2026 Rabie, El-Nashar, George, Khaleel, Badi, Hassab, Eldehna and Mostafa
Add phentermine at the lowest effective dose, typically 8 mg three times daily or 15 mg once daily in the morning
doi: 10.1016/j.ejphar.2009.12.023 115 CastellanaMCignarelliABresciaFPerriniSNatalicchioALaviolaLet al
All studies should follow appropriate institutional research standards, including oversight from Institutional Review Boards (IRB) or Institutional Animal Care and Use Committees (IACUC) where applicable