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The drug performed better on all secondary endpoints as well, including a greater percentage of people losing at least 15% of their weight (roughly a third of those on the highest dose achieved this)
"In future studies we will aim to identify what healthcare providers can do to optimize GLP-1 outcomes, identify which patients are better treated with bariatric surgery versus GLP-1s, and determine the role out-of-pocket costs play in treatment success," said study senior author and bariatric surgeon Karan R
Semaglutide 2.4 mg (Wegovy) and liraglutide 3.0 mg (Saxenda) are licensed for weight management in adults with BMI 30 kg/m or 27 kg/m with weight-related comorbidities
Ipamorelin provides immediate GH release, CJC-1295 sustains elevation over days, and IGF-LR3 directly activates tissue receptors
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