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In DR, GLP-1RAs vascular stabilization effects (via RhoA/ROCK inhibition) (Wei et al., 2022) could complement anti-VEGF therapy, yet their interaction in modulating angiogenesis remains unexplored

To remove any excess antibodies, 0.01 M TBS with 0.1% Tween 20 was added in 10 times the volume of the conjugate mixture and was centrifuged at 9000 g for 10 min

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Plasma glucose also tended to decrease during the first 48 h (162126 mg/dl), accompanied by a parallel decrease in plasma insulin levels (184118 pmol/L) consistent with the insulinomimetic effects of GLP-1

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