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When combined with caloric restriction, they support an additional 2-4 pounds of weight loss per month compared to diet alone
Treatment doses depend on the cause: pernicious anaemia typically requires intramuscular hydroxocobalamin 1,000 micrograms three times weekly initially, whilst dietary deficiency may be treated with oral cyanocobalamin 50150 micrograms or 1,000 micrograms daily
The peptide is most commonly administered once daily in the morning on an empty stomach, though some protocols use twice-daily dosing
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