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Conclusion: In congestive hepatopathy, mechano-stress in the liver sinusoids activates YAP/TAZ and enhances CTGF expression in LSECs, which may contribute to the development of liver fibrosis and portal hypertension
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462 Magnetic resonance perfusion imaging studies have identified increased thalamic vascularity in patients with PDPN during resting states, likely reflecting heightened neuronal activity
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In addition, GLP-1 activation in astrocytes by GLP-1R altered cellular glucose metabolism, revealing a novel mechanism by which GLP-1R improves cognitive function in patients with AD (Zheng et al., 2021)
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