357 In addition, cGAMP synthesized by cGAS can be transmitted to adjacent cells via gap junctions, engaging plasma membrane-bound STING and triggering a similar response
Even though the milling of whole grains into flour can break open all the grains cell walls, whole-grain bread is still better than white bread, because whole-grain at least has extra fiber that makes it down to our colon
Drug Resistance When weight-loss medications fail to deliver results, users may opt for stronger, more potent drugs, leading to drug resistance
Sahni doesnt believe in a one-size-fits-all dose
New in ADA 2026 Pharmacologic Prevention Metformin should now be considered not just for prediabetes, but specifically to prevent hyperglycemia in high-risk patients initiating PI3K inhibitors (e.g., alpelisib, inavolisib) or high-dose glucocorticoids, two brand new indications added in 2026