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Additionally, intraperitoneal administration of GLP-1 at supraphysiological doses elicited an anti-adipogenic effect in rats (72), making GLP-1 a potential target for obesity treatment

After more vigorous pipetting, cells were pelleted by centrifugation at 400 RCF for 5 min and seeded onto a 24-well plate

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Use a fresh syringe per session

This DPP-4 inhibitor is contraindicated in this patient group on the basis of the respective cardiovascular safety study that has shown a significant increase of hospitalization for heart failure as secondary endpoint in the saxagliptin arm (63, 66)