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A high percentage of cells in S-phase is associated with a better clinical response to MTX (11) and is accompanied by increased expression of genes involved in nucleotide biosynthesis, such as TYMS , CPTS , and an MTX target enzyme, DHFR ( 11)
2020;15(4):e0231209
First, the area to be treated is marked by the doctor while the patient is standing to ensure that trouble spots are clearly defined
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