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NRTIs interfere with mitochondrial metabolism by reducing neuronal mitochondrial DNA synthesis leading to a disruption of oxidative metabolism [1,4-6]

Individuals with SMIs experience premature and excess mortality, with years of life lost often estimated between 5 and 25 years, largely due to earlier onset and substantially higher rates of CVD

Barkley, R

The statistical difference between the two groups (p=0.002) provides strong evidence for our conclusions

Because of the growing interest in this field and the increasing amount of scientific research being published, I wanted our students to have a solid understanding of both the benefits and limitations of these therapies