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This disruption leads to a loss of fibroblast spreading and mechanical force, resulting in an "aging" phenotype [19]

The most defensible statement is narrow: severe deficiency of methionine and choline impairs hepatic fat export and causes steatosis the classic methionine-choline-deficient (MCD) diet reliably induces fibrosing steatohepatitis in rodents [4] [5]

Do not wait for routine labs Severe abdominal pain, persistent vomiting, fainting, dehydration, chest pain, or allergic symptoms need medical review