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Its intracellular concentration usually indicates oxidative cellular stress, as the latter profoundly affects the cellular thiol balance, usually causing a decrease in the cellular GSH/GSSG ratio
Dalle-Donne, I., Rossi, R., Colombo, R., Giustarini, D
Immunization of sheep against Fasciola gigantica with glutathione S-transferase [PMID: 11900929] Laboratory literature summary: Immunization of sheep against Fasciola gigantica with glutathione S-transferase
Patients with ACOX1 (p.N237S) exhibit loss of glia, Schwann cells and neurons
Cureus 17(10): e94838
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