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This aging mechanism is closely related to various common diseases, including atherosclerosis, hypertension, chronic obstructive pulmonary disease, diabetes, and neurodegenerative disorders (Liu et al., 2022
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Pyroglutamic acid as biomarker of APAP-induced liver injury Acute APAP hepatotoxicity has been reported as a common cause of metabolic acidosis, which sometimes occurs prior to liver injury (Flanagan and Mant 1986
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This analysis highlights the complexity of transmission of information within the receptor, with differences in the persistence of peptidereceptor interactions and receptor interactions linking the peptide and G protein-binding sites resulting in different efficacy (and bias) of different peptides agonists
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