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Your provider will help determine which option aligns best with your symptoms and goals
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Recent studies show patients taking semaglutide and other semaglutide drugs have more than a fourfold higher risk of developing NAION compared to those not taking GLP-1 medications, and the World Health Organization issued warnings in June 2025 about this serious complication
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This creates a two-pronged suppression effect
![do glp 1 medications cause muscle loss GLP-1 Explained glp-1_analogs [TUSOM | Pharmwiki]](https://cdn.prod.website-files.com/62aec59ac7c1e4f6f1719e4a/690caf17e931f1636f248831_CgUyxwN_4SFD0KP71JhVsyyjnwGtK-Z4rKs0J_oB-Ac.png)
There were no significant differences between groups in terms of fatigue and other toxicities
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Patients should discuss any thyroid symptoms with their healthcare provider (as a precaution based on animal studies)
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