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A primary cause is the medications effect on gastric motility, leading to slower digestion and a sensation of fullness that may reduce overall caloric intake
While human cognitive studies are still needed, the preliminary data is encouraging
The dose-response question is unanswered While the meta-analysis showed that 5 mg produced significant CRP reduction, we do not know where the minimum effective anti-inflammatory dose falls
Lancet 394:131138 Tuttle KR, Lakshmanan MC, Rayner B, Busch RS, Zimmermann AG, Woodward DB et al (2018) Dulaglutide versus insulin glargine in patients with type 2 diabetes and moderate-to-severe chronic kidney disease (AWARD-7): a multicentre, open-label, randomised trial
113: 499506 Sima AAF, Brismar T
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