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Safety Considerations and Side Effects GLP-1 agonists are generally well-tolerated, with common side effects including nausea, vomiting, and diarrhea, especially during the initial stages of treatment
Patients who are using skin lightening products or undergoing other skin lightening treatments should refrain from exposing themselves as best they can throughout the duration of treatment to avoid risking skin damage, including skin cancer
Potential side effects include local irritation of the nasal passages
While the body does produce natural GLP-1, this endogenous hormone is rapidly broken down by the enzyme dipeptidyl peptidase-4 (DPP-4) within minutes of secretion, making it unsuitable as a therapeutic agent without pharmaceutical modification
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