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Then, the rate-limiting enzyme in arginine synthesis, argininosuccinate synthetase 1 (ASS1), catalyzes the conversion of citrulline and aspartate into argininosuccinate, which is then cleaved into arginine and fumarate by argininosuccinate lyase (ASL) (Figure 1)

Less common symptoms include: Headaches

Serious side effects include muscle weakness, extreme thirst, confusion, shortness of breath, headache, exhaustion, reddening of the skin, and a fast or irregular heartbeat

When combined with the groundbreaking GS441524 treatment developed by CureFIP US, there is even greater potential for improved outcomes and the possibility of a true cure for FIP

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