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Beyond the toxic gain-of-function effects of mHTT, HD pathogenesis involves a range of interconnected mechanisms, including mitochondrial dysfunction, transcriptional dysregulation, impaired autophagy, proteostasis failure, excitotoxicity, oxidative stress, and chronic neuroinflammation [3843]

Taking them provides micronutrients that your body may not always get from food alone

doi:10.1098/rsob.120061

When it binds with copper (Cu), it activates enzymes responsible for: connective tissue formation antioxidant defense cellular respiration It also regulates free copper ions to prevent oxidative stress, keeping the system balanced rather than reactive