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The best-supported benefits are weight reduction, BMI reduction, improved insulin resistance, and some improvements in androgen-related markers

For a 16:8 eating window with three meals: Meal 1 (breaking the fast): 30 to 40 grams of protein Meal 2 (midday): 30 to 40 grams of protein Meal 3 (end of eating window): 30 to 40 grams of protein That puts you at 90 to 120 grams of protein minimum, before protein-containing snacks

Access of the HMG coenzyme A substrate is thus prevented because of the presence of the statin in the binding pocket of the enzyme, 13 ultimately inhibiting both mevalonic acid and cholesterol synthesis (Figure)

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Lancet Diabetes Endocrinol 2024;12:51-60.PubMed 54