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Results PAGln is elevated in patients with alcohol use disorder In a cohort of individuals who were determined to be heavy drinkers (HD) based upon their Alcohol Use Disorder Identification Test Corrected (AUDIT-C) score, we analyzed serum samples using LC-MS/MS for semi-quantitative levels of circulating metabolites as previously described 13
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This is concerning because loss of skeletal muscle can lead to decreased strength, reduced functional capacity, and a lower resting metabolic rate, potentially making weight regain more likely after medication discontinuation
