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However, three overdose patients had APAP-CYS concentrations that were of the same order of magnitude as those observed with therapeutic dosing

[1] [2] Elevated methylmalonic acid levels may also indicate a deficiency

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doi: 10.1016/j.tibs.2022.10.002 112 ZhangTTsutsukiHIslamWOnoKTakedaKAkaikeTet al