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Vegetarian and plant-based diets in health and disease prevention (ed Franois Mariotti) 135

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Studies have shown that epileptiform seizures may initially originate from ion channel dysfunction caused by various stress events such as central nervous system injury, and that astrocyte proliferation and inflammatory responses play important roles in the pathological process of neuronal network excitation and inhibition imbalance, which is a self-perpetuating process

Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2-related factors 1 and 2 (NRF1 and NRF2)