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Notably, the full spectrum of clinical features associated with B12 deficiency is much broader, is nonspecific, and may occur as a consequence of other diseases

Biochemical regulation of mammalian AMP-activated protein kinase activity by NAD and NADH [PMID: 15465812] Laboratory literature summary: Biochemical regulation of mammalian AMP-activated protein kinase activity by NAD and NADH

[20] Pernicious anemia [edit] Pernicious anemia is a disease caused by an autoimmune response that produces antibodies that attack the parietal cells in the stomach lining, preventing them from creating intrinsic factor needed for the absorption of vitamin B 12

In a pool of two ZEPBOUND clinical trials for weight reduction (Studies 1 and 2), cholelithiasis was reported in 1.1% of ZEPBOUND-treated patients and 1% of placebo-treated patients, cholecystitis was reported in 0.7% of ZEPBOUND-treated patients and 0.2% of placebo-treated patients, and cholecystectomy was reported in 0.2% of ZEPBOUND-treated patients and no placebo-treated patients

Vitamin B12 supplementation orally and intramuscularly in people with obesity undergoing gastric bypass