J Physiol Paris 91:113122 Keremi B, Lohinai Z, Komora P, Duhaj S, Borsi K, Jobbagy-Ovari G, Kallo K, Szekely AD, Fazekas A, Dobo-Nagy C et al (2009) Antiinflammatory effect of BPC 157 on experimental periodontitis in rats
Those suffering from B12 deficiency have been known to have lower than normal bone mineral density, which can lead to osteoporosis over time
The rationale was that direct delivery to the joint would maximize local efficacy while minimizing systemic exposure
The articles from Drugs.com, WebMD, MedicineNet, and Biom do not reference any study to back up their claim, whereas the other three articles all cite an experiment performed on brewers yeast called Impact of glutathione metabolism on zinc homeostasis in Saccharomyces cerevisiae
Sources Sonthalia S, Daulatabad D, Sarkar R