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Pharmacological Characterisation of CR6086, a Potent Prostaglandin E(2) Receptor 4 Antagonist, as a New Potential Disease-Modifying Anti-Rheumatic Drug
He D, He X, Wang K, et al
Its ability to penetrate the BBB, its metabolic stability, and its significant efficacy in restoring cognitive and motor functions in animal models of AD and PD, likely through modulating the HGF/c-Met system, position it as a highly promising therapeutic candidate for these debilitating neurodegenerative diseases [2]
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