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SF-1 a key player in the development and differentiation of steroidogenic tissues
Promote renal calcium reabsorption Renal tubular calcium transport: upregulate the expression of renal tubular calcium channel (TRPV5), reduce urinary calcium excretion by 30% -40%, increase blood calcium concentration, and increase bone calcium deposition Evidence from preclinical studies on AOD 9604 bone protection (animal experiments) Postmenopausal osteoporosis (OVX rat model) Experimental Design: Animal: 6-month-old female SD rats underwent bilateral ovariectomy (OVX) to establish a postmenopausal osteoporosis model
After ligand immobilization, analytes were injected at different concentrations, i.e., 33 M, 100 M, and 300 M, into a moving stream of buffer (Valentini et al., 2022
The results might not apply to all women
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