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In patients receiving semaglutide 1.0 mg, both escalation to semaglutide 2.4 mg and switching to tirzepatide 5 mg were associated with high probability of improved weight loss
Both activate GLP-1 receptors, and combining them increases side effect risk, particularly nausea and vomiting, without providing additional benefit
Primers for SYBR Green PCR were from Eurofins Scientific (sequences are provided in ESM Table 1)
Inflammasomes and cancer: The dynamic role of the inflammasome in tumor development
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