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In addition, pharmacological therapy interferes with carnitine absorption, synthesis, and excretion [17, 18]
Some patients may successfully maintain their weight on lower doses depending on their individual response
GLP-1 originating from the gut has a very short circulating half-life of only 12 min due to its rapid inactivation by the enzyme dipeptidylpeptidase-4 (DPP-4) and subsequent clearance through the kidneys
For people considering long-term GLP-1 use, the safety data is encouraging
Exp Biol Med (Maywood), 2019
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