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The gradual conversion of these derivatives to active Vitamin C upon application provides sustained antioxidant and brightening effects
Clinical ophthalmology (Auckland, N.Z.), 17, 20452062
Importantly, our study has several limitations
In ARPE-19 cells the addition of glucose increased intracellular ROS levels and lowers the expression of the antioxidant genes SOD2, CAT, and HMOX1
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