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Invocamos nuestra Regla de los 7 Aos porque los nuevos frmacos se prueban en un nmero relativamente pequeo de personas antes de su comercializacin y es posible que los efectos adversos graves o las interacciones farmacolgicas potencialmente mortales no se detecten hasta que cientos de miles de personas hayan tomado el nuevo frmaco
A prior single-center, retrospective study of patients with overweight or obesity found mean weight loss of 3.4% and 7.0% among semaglutide and tirzepatide patients, respectively, without diabetes after 6 months of follow-up
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The medication is initiated at a lower dose and gradually titrated upward to minimize gastrointestinal side effects, which are the most commonly reported adverse reactions
