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doi:10.1172/JCI106182

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Importantly, microglia in this activated state also secrete pro-inflammatory cytokines such as TNF-, IL-1, and IL-6, which further amplify ROS production and reinforce the inflammatory state

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Biochim Biophys Acta 1862(11):23332342 Seitomer E, Balar B, He D, Copeland PR, Kinzy TG (2008) Analysis of Saccharomyces cerevisiae null allele strains identifies a larger role for DNA damage versus oxidative stress pathways in growth inhibition by selenium