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ASCO 2011, 2011
In vitro , overexpression of PACS-2 in HK-2 cells restores reticulophagy via TFEB/family with sequence similarity 134 member B pathway ( Autophagy disruption is caused by multiple-level abnormalities in upstream signaling pathways (117, 152)
This product is provided strictly for research purposes
It allows it to keep protecting cells from oxidative stress
When macrophages are recruited by adipose tissue due to the overexpression of monocyte chemoattractant protein 1 (MCP1, a chemokine ligand also known as CCL2), hepatic insulin resistance is observed with increased TNF expression in adipose tissue, but without any change in body weight or adiposity [148]
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