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Early trial data shows weight loss exceeding 24% at higher doses
The main chemical constituents are benzaldehyde (19.03%), phenol (13.22%), 2-pentylfuran (7.42%) and cubeba olefine (7.31%) (Zhou et al., 2018)
Changing Cys25 to either serine or alanine increased its p K a to 4.9 and 5.9, respectively
It has not received approval from Health Canada for therapeutic use, meaning it cannot be prescribed or marketed as a treatment
Unlike the allosteric activator compound 102 , the GPX4 inhibitor RSL3 binds to the substrate binding site
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