Before prescribing oral semaglutide, your provider will review your medical history to ensure it is safe and suitable for you, especially if you have a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2
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Additional factors warranting consideration include active malignancy, recent surgery or trauma, use of oestrogen-containing contraceptives or hormone replacement therapy, smoking, and certain inflammatory conditions such as inflammatory bowel disease
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It is a foundational treatment for several autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis