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Numerous cysteine-based redox switches have been found to underpin many different signalling systems and regulate physiological outputs across kingdoms 22,23

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(Reference Tabatabaee, Alavian and Ghalichi113) concluded that 3 months of supplementation with 550 mg/d of GTE significantly reduced BMI in obese patients with non-alcoholic fatty liver disease

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When the vascular wall is stimulated by hypoxia, mechanical damage, or platelet-derived growth factor (PDGF-BB), the transcription coactivator MYOCD and the nuclear transcription factor EIkI compete for the same binding site on the serum response factor, and the contractile phenotype-responsive SRF-MYOCD complex is converted to the synthetic phenotype-responsive SRF-ELK1 complex, prompting the VSMCs to transform from a contractile phenotype to a synthetic phenotype [43, 44]

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