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The glucagon receptor activation drives this effect by promoting hepatic fat oxidation, essentially telling the liver to burn its stored fat reserves
MEDI0382, a GLP-1 and glucagon receptor dual agonist, in obese or overweight patients with type 2 diabetes: a randomised, controlled, double-blind, ascending dose and phase 2a study
The other is a triple agonist
Additionally, 86.4% of individuals in this study lost at least 5% of their body weight
Guo, J., et al
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