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This mitochondrial fission triggers an upregulation of CHAC1/BOTCH through the transcription factor NRF2 and ROS signaling, which in turn inhibits stem cell self-renewal and promotes cell differentiation (Khacho et al., 2016)
It helps ensure that follicles remain active and receive the nutrients they need
[PubMed ID: 18825537]
Upon measuring grip strength, the researchers found that treatment on its own in sedentary mice increased grip strength by about 25%, compared to exercise alone increasing grip strength by about the same percentage
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