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doi: 10.1016/j.diabres.2012.09.008 210 WenjingHShaoYYuYHuangWFengGLiJ

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Tirzepatide actually activates both GLP-1 and GIP receptors, making it a dual-acting medication with a somewhat stronger effect on the digestive system

Specifically, ATF-4 enhances stress resistance and promotes longevity in worms by upregulating the transsulfuration enzyme CTH-2, increasing hydrogen sulfide (H 2 S) production (Statzer et al., 2022)