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Gan Y, Zhang Y, Digirolamo DJ, Jiang J, Wang X, Cao X, Zinn KR, Carbone DP, Clemens TL, Frank SJ
Unlike other vitamins, the absorption of vitamin B12 depends on a protein produced in the stomach called intrinsic factor
Heavier individuals may need higher absolute doses to achieve equivalent tissue concentrations, while lighter individuals may find lower doses sufficient
One proposed mechanism involves adenylyl cyclase activity, which could raise cyclic AMP (cAMP) levels and activate protein kinase A (PKA)
Consistency is everything daily use for several months is what the research is based on
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