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Because they are, and not just in North America
Research indicates that VEGF levels in the serum of patients with DR progressively rise as the disease worsens, highlighting its critical role in the development of DR and its correlation with disease severity
The A-NPs@(SHK+Ce6) nanosystem incorporates CaCO3 nanoparticles to buffer excess H+ ions and alleviate suppressive conditions, while the loaded SHK peptide inhibits lactate production and synergizes with photodynamic therapy to repolarize TAMs toward the M1 phenotype (53)
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The rescued protein expression was evaluated by immunoblotting using specific antibodies
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