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While acknowledging the strengths of the study, such as participant criteria, low drop-out rates and high adherence, the researchers also acknowledged limitations, including the relatively short intervention duration and the absence of a third intervention group receiving synbiotics alongside a placebo

A recent case report documented toxic elevations in 6-thioguanine levels following tirzepatide initiation (107)

Metabolism (1977) 26:3516

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Personalized dosing is crucial for GLP-1 medications, as it ensures your dosage aligns with your bodys needs, weight loss goals, medical history, and tolerance levels