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Harvie MN, Pegington M, Mattson MP, Frystyk J, Dillon B, Evans G, Cuzick J, Jebb SA, Martin B, Cutler RG, Son TG, Maudsley S, Carlson OD, Egan JM, Flyvbjerg A, Howell A

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These findings suggest that Bdnf expression in the hippocampus is sensitive to fluctuations in leptin availability and leptin signaling, serving as a finely tuned neural component of the adipose-brain axis

Isolated T cells were activated with human T activator CD3/CD28 Dynabeads (Life Technologies, 11131D) at a 1:1 cell-to-bead ratio for 24 h before transduction