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Clinical research suggested doses in the range of 1-10mcg per kilogram of body weight showed efficacy, though most protocols standardized around 4-6mcg/kg for practical application

Low energy Tingling sensation or numbness in hands or feet A swollen, red cracked tongue Mood changes Trouble concentrating and remembering things Megaloblastic anemia People at risk for Vitamin B12 Deficiency: People with a deficiency of intrinsic factor

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Loading regimens involve 1 mg three times weekly for two weeks, or alternate-day dosing if neurological symptoms are present