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Composed of a linear 13-amino-acid sequence ([N-acetyl-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2]), Melanotan 1 features strategic molecular modificationsspecifically the substitution of Norleucine for methionine at position 4, and D-Phenylalanine for L-phenylalanine at position 7