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GLP-1(2836) enters human coronary artery endothelial cells (caECs) through macropinocytosis and acts directly on mouse and human coronary artery smooth muscle cells (caSMCs) and caECs, resulting in soluble adenylyl cyclase Adcy10 dependent (sAC-dependent) increases in cAMP, activation of protein kinase A, and cytoprotection from oxidative injury
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