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AOD-9604 has been the subject of multiple clinical trials
J.GeW.ZhaiQ
In vivo proof of a powerful proinflammatory mechanism and a new anti-inflammatory strategy
The resulting GSH or homoglutathione (-L-glutamyl-L-cysteinyl--alanine) conjugates were usually much less toxic and more water-soluble than the original xenobiotics (Brown and Neighbors, 1) (Bartling et al., 2002
Ultimately, the radical chain reactions will be blocked by the antioxidant enzymes superoxide dismutase (SOD) in association with catalase or GPX that determines the complete free radicals scavenging (Winterbourn, 1993)
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