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10.1146/annurev-physiol-021113-170317 Annu

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GLP-1RA intervention was associated with a reduction in insulin levels at h after OGTT when compared to those given metformin or placebo (MD = 27.88

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It is also crucial to recognize that an increasing number of both preclinical and clinical research studies indicate that some therapeutic benefits of GLP-1 RAs, especially their anti-inflammatory and cytoprotective effects, may not be entirely connected to their primary use related to body weight