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This results from a tyramine-induced depletion of norepinephrine normally present in the readily releasable vesicle pool, and replacement of vesicular norepinephrine with tyramine (which functions as a false- or pseudo- neurotransmitter), which when released has no effect on postsynaptic adrenergic receptors (Figure 1)

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For best results,use the cream twice daily, in the morning and evening

GHK-Cu is photolabile as a copper(II) peptide complex, so keep both lyophilised vials and reconstituted solution protected from UV and fluorescent light, using amber or foil-wrapped vessels for aliquots