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Acta 1773 , 12851298 (2007)
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Buckle up, we're about to spill the tea on this fantastic molecule and why your body loves a good dose of it
Anti-inflammatory NF-B Modulation MC1R and MC3R activation by melanocortin peptides has been shown to suppress NF-B nuclear translocation and downregulate pro-inflammatory cytokine production (TNF-, IL-6, IL-1) in macrophage and keratinocyte models, suggesting a role in cutaneous inflammatory signaling research (Luger et al., Journal of Investigative Dermatology, 1997)
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